منابع مشابه
Polio vaccines and polio immunization in the pre-eradication era: WHO position paper--recommendations.
This article presents the WHO recommendations on the use of polio vaccines excerpted from the recently published Polio vaccines and polio immunization in the pre-eradication era: WHO position paper. This document replaces the WHO position paper entitled Introduction of inactivated poliovirus vaccine into oral poliovirus vaccine-using countries published in the Weekly Epidemiological Record in J...
متن کاملContamination of polio vaccines by monkey viruses and other microorganisms
Polio viruses for the production of polio vaccines have been cultured on monkey kidney tissue and cell lines. These are naturally infected by monkey (simian) viruses and other microorganisms and agents (protozoans, amoebas). They cause, and/or are a co-factor, in a great variety of cancers and other diseases. The methods used to “clean-up” the animal tissue and/or microorganisms of these undesi...
متن کاملAlternative administration routes and delivery technologies for polio vaccines.
Global polio eradication is closer than ever. Replacement of the live attenuated oral poliovirus vaccine (OPV) by inactivated poliovirus vaccine (IPV) is recommended to achieve complete eradication. Limited global production capacity and relatively high IPV costs compared to OPV spur the need for improved polio vaccines. The target product profile of these vaccines includes not only dose sparin...
متن کاملExperimental oral polio vaccines and acquired immune deficiency syndrome.
The simian immunodeficiency virus (SIV) of the common chimpanzee is widely acknowledged as the direct ancestor of HIV-1. There is increasing historical evidence that during the late 1950s, kidneys were routinely excised from central African chimpanzees by scientists who were collaborating with the polio vaccine research of Dr Hilary Koprowski, and sent - inter alia - to vaccine-making laborator...
متن کاملChimpanzees Inoculated with Cytomegalovirus Contaminated Polio Vaccines may Explain
The genomic sequences of HIV-1 isolates are closely related to the sequences of simian immunodeficiency viruses of chimpanzees SIV (cpz) [1]. It is widely presumed, therefore, that a SIV (cpz)-derived virus can evolve into HIV. The time at which humans initially became infected with SIV (cpz) or with a SIV (cpz)-derived virus is less certain. Yet this is clearly relevant to the likely mode of v...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature
سال: 1995
ISSN: 0028-0836,1476-4687
DOI: 10.1038/376458c0